White Sox vs. Cubs odds, line: 2021 MLB picks, Sunday Night Baseball predictions for August 8 from top model

The Chicago White Sox will look for the three-game sweep against the rival Chicago Cubs in a key interleague matchup on Sunday Night Baseball. The White Sox (65-46), first in the American League Central, have won two in a row and four of six. They have a 10.5 game lead over the second-place Cleveland Indians. The Cubs (52-60), meanwhile, are fourth in the National League Central and have lost three in a row and five of six.

First pitch from Wrigley Field is set for 7:09 p.m. ET. The White Sox lead the all-time series 71-65, including a 37-32 edge in games played on the north side. The White Sox are a -177 favorite on the money line in the latest White Sox vs. Cubs odds from Caesars Sportsbook, while the over-under for total runs scored is 10. Before making any Cubs vs. White Sox picks, check out the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, is a profitable 140-113 on top-rated MLB money-line picks through 18 weeks in the 2021 season. It also had a banner 2019 season, the league’s last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. Anyone following it has seen some huge returns.

Now, the model has locked in its White Sox vs. Cubs picks and predictions. You can visit SportsLine now to see its MLB picks. Here are the MLB odds today and betting trends for Cubs vs. White Sox:

• White Sox vs. Cubs money line: White Sox -177, Cubs +162
• White Sox vs. Cubs run line: White Sox -1.5
• White Sox vs. Cubs over-under: 10 runs
• CWS: The White Sox are 4-0 in their last four Sunday games
• CUBS: The over is 4-0-1 in the Cubs’ last five games as a home underdog

Why you should back the White Sox

The White Sox are expected to send right-hander Dylan Cease (8-6, 3.92 ERA) to the mound on Sunday night. Cease was outstanding in his last outing, allowing just one hit in six innings in a 7-1 win over the Kansas City Royals. He walked two and struck out 11. He has two career starts against the Cubs, going 0-2 with a 5.91 ERA. But he will be facing a vastly different lineup this time around. The Cubs traded several of their best players at the trade deadline, including three of their top batters in Kris Bryant, Javier Baez and Anthony Rizzo.

Offensively, second baseman Cesar Hernandez has been on fire. He is 3-for-7 with two homers and three RBIs in the series and has hits in nine of his past 11 games, including six multi-hit games. For the season, he is batting .240 with 20 homers, 50 RBIs and 65 runs scored. In 44 career games against the Cubs, he is batting .288 with nine doubles, two triples, three homers and 17 RBIs.

Why you should back the Cubs

The Cubs are expected to start right-hander Zach Davies (6-8, 4.79 ERA). He has been a dependable starter this season with very few blow-up games. Unfortunately for Davies, he had one of those starts in his last outing when he allowed seven earned runs in four innings pitched at Colorado on Tuesday. But for his few bad games, he has also pitched some gems. One was at Los Angeles when he pitched six innings of no-hit ball against the Dodgers on June 24. 

Second baseman David Bote has been hot of late with hits in four of his last five games. In Saturday’s 4-0 loss to the White Sox, Bote was 2-for-4 with a double. In 62 games, Bote is hitting .209 with six homers, 29 RBIs and 21 runs scored. He has had success against the White Sox with two homers and eight RBIs in 14 career games against them.

How to make Cubs vs. White Sox picks

SportsLine’s model is leaning under on the total, as the simulations project both teams combine for 9.3 runs. The model also says one side of the money line has the value. You can only get that Sunday Night Baseball pick at SportsLine. 

So who wins White Sox vs. Cubs? And which side of the money line has all the value? Visit SportsLine now to see which side of the Cubs vs. White Sox spread to jump on, all from the advanced model that has crushed its MLB picks in 2021.